Double-Exposure to Acute Stress and Chronic Family Stress is Associated With Immune Changes in Children With Asthma

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Double-exposure to acute stress and chronic family stress is associated with immune changes in children with asthma.

OBJECTIVE To understand how psychological stress heightens risk for asthma flare-ups, we examined the relationship between acute stress, chronic family stress, and the production of asthma-related cytokines. METHODS Seventy-one children with asthma and 76 medically healthy children completed interviews regarding life stress, and peripheral blood samples were collected. After mononuclear cells...

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Socioeconomic status associated with exhaled nitric oxide responses to acute stress in children with asthma.

Although psychosocial stress has been linked to clinical asthma outcomes, controlled, laboratory paradigms that test associations between psychosocial stress and markers of airway inflammation in humans are lacking. There is also little known about how individual background characteristics may affect variability across individuals in asthma-relevant inflammatory and pulmonary responses to stres...

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Stress in Children and Adolescents with Asthma

Objective: to evaluate stress in children and adolescents with asthma and its association with clinical and psychosocial features. Methods: cross-sectional study conducted with asthmatic children and adolescents between 7 and 12 years old, seen at the pediatric pulmonary outpatient clinic. The Stress Childhood Scale, the Criterion of Economic Classification Brazil and a questionnaire were used ...

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Neurobehavioral risk is associated with gestational exposure to stress hormones.

The developmental origins of disease or fetal programming model predict that early exposures to threat or adverse conditions have lifelong consequences that result in harmful outcomes for health. The maternal endocrine 'fight or flight' system is a source of programming information for the human fetus to detect threats and adjust their developmental trajectory for survival. Fetal exposures to i...

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Metabolic Syndrome Is Associated with Increased Oxo-Nitrative Stress and Asthma-Like Changes in Lungs

Epidemiological studies have shown an increased obesity-related risk of asthma. In support, obese mice develop airway hyperresponsiveness (AHR). However, it remains unclear whether the increased risk is a consequence of obesity, adipogenic diet, or the metabolic syndrome (MetS). Altered L-arginine and nitric oxide (NO) metabolism is a common feature between asthma and metabolic syndrome that ap...

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ژورنال

عنوان ژورنال: Psychosomatic Medicine

سال: 2009

ISSN: 0033-3174

DOI: 10.1097/psy.0b013e318199dbc3